If you have the point and the polygon, you can just adjust whether the point is contained by the polygon like this:
bool isContains = polygon.Contains(point);
Please let me know whether I understand your requirement correct. If you have a lot of polygons, you can build a simple function and loop all polygons for this.
If your polygons is in the same layer, here I just put an inmemory feature layer as example, you can do it like this: